Yes, facade greening can even achieve that. Unloved graffiti is a problem against which cities struggle against in vain. Climbing trees and shrubs at the base of walls can be an effective protection, because there is no space for graffiti on vegetated walls! Also already existing graffiti can be covered with plants. So can greening be an effective facade protection... affordable, low maintenance and ecologically valuable? Here you will find image examples and details for graffiti protection by vegetation.
"An ounce of prevention is worth a pound of cure." Most of the plants will only protect the ground/base area, and then regular pruning is necessary. Often some wires, according to the cable systems 1020, 1060, or 8010 are required to reign in the stubborn instincts of some plants and affix them to the wall. But an easy kit is usually sufficient. Also painted plants, i.e. floral motifs by artists, are an effective protection against graffiti; see below.
Sometimes it's worth it... In order to protect the base of the wall after graffiti has been removed, roses and Pyracantha are planted. It's no fun in the dark for sprayers to run up against their sharp thorns that tear into expensive brand name apparel... The evergreen is also a worthwhile possibility against graffiti. Small, low maintenance winter creepers remain limited with only moderate growth, yet without a lot of trimming needed on the base areas.
The removal of graffiti is expensive, and stucco or protective coatings may be removed with the grafitti in the process. This could hinder the water vapor permeability of a wall, which in turn can lead to delamination/spalling in certain kinds of masonry. Therefore, it may be useful to leave graffiti on the wall, and to conceal it by greening up. Ivy, Virginia creeper, and Boston ivy can rapidly green up a grafittied wall. Careful though-- overgrowth can possibly create structural damage.